EST-PAC a web package for EST annotation and protein sequence prediction
نویسندگان
چکیده
منابع مشابه
EST-PAC HPC – a web portal for high-throughput EST annotation and protein sequence prediction
Expressed Sequence Tags (ESTs) are short DNA sequences generated by sequencing the transcribed cDNAs coming from a gene expression. They can provide significant functional, structural and evolutionary information and thus are a primary resource for gene discovery. EST annotation basically refers to the analysis of unknown ESTs that can be performed by database similarity search for possible ide...
متن کاملESTExplorer: an expressed sequence tag (EST) assembly and annotation platform
The analysis of expressed sequence tag (EST) datasets offers a rapid and cost-effective approach to elucidate the transcriptome of an organism, but requiring several computational methods for assembly and annotation. ESTExplorer is a comprehensive workflow system for EST data management and analysis. The pipeline uses a 'distributed control approach' in which the most appropriate bioinformatics...
متن کاملAnalysis of EST-driven gene annotation in human genomic sequence.
We have performed a systematic analysis of gene identification in genomic sequence by similarity search against expressed sequence tags (ESTs) to assess the suitability of this method for automated annotation of the human genome. A BLAST-based strategy was constructed to examine the potential of this approach, and was applied to test sets containing all human genomic sequences longer than 5 kb ...
متن کاملSEAN: SNP prediction and display program utilizing EST sequence clusters
SEAN is an application that predicts single nucleotide polymorphisms (SNPs) using multiple sequence alignments produced from expressed sequence tag (EST) clusters. The algorithm uses rules of sequence identity and SNP abundance to determine the quality of the prediction. A Java viewer is provided to display the EST alignments and predicted SNPs.
متن کاملESTAnnotator: a tool for high throughput EST annotation
In high throughput sequence analysis, it is often necessary to combine the results of contemporary bioinformatics tools, because no individual tool alone computes all the requested information. ESTAnnotator is a tool for the high throughput annotation of expressed sequence tags (ESTs) by automatically running a collection of bioinformatics applications. In the first step, a quality check is per...
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ژورنال
عنوان ژورنال: Source Code for Biology and Medicine
سال: 2006
ISSN: 1751-0473
DOI: 10.1186/1751-0473-1-2